INTRODUCTION

CONIMUNE ME 50MG contains Cyclosporine which belongs to the group of medicines called immunosuppressive agents. Immunosuppressive agents are drugs that suppress or reduce the strength of the body’s immune system. It is used to prevent graft rejection in patients who have had an organ transplant, bone marrow, and stem cell transplantation.

It can also be used to treat various autoimmune diseases like severe rheumatoid arthritis, nephrotic syndrome (kidney disease), eye problems (endogenous uveitis, including Behçet's uveitis), and skin diseases (atopic dermatitis, or eczema and psoriasis). Cyclosporin blocks the development of cells that attack the affected transplanted tissue and suppress abnormal immune function thus preventing the rejection of transplanted organs.

Limit your exposure to sunlight and UV light by wearing protective clothing and by applying sunscreen to prevent skin cancer. Avoid the consumption of alcohol or grapefruit juice while taking this medicine. This medicine should not be given to children for any non-transplant disease, except for nephrotic syndrome. Do not take this medicine if you have any uncontrollable infection or any type of cancer. Consult your doctor for advice.

USES OF CONIMUNE ME 50MG

• Prevents the rejection of transplanted organs
• Treats severe rheumatoid arthritis
• Treats nephrotic syndrome (kidney disease)
• Treats eye problems such as endogenous uveitis, including Behçet's uveitis
• Treats skin diseases such as atopic dermatitis, or eczema and psoriasis)

HOW TO CONTINUE ME 50MG WORKS

Cyclosporine works by inhibiting the production of various cytokines involved in the regulation of T-cell activation. These effects of cyclosporine on T cells and on connective tissue cells can produce a range of cytokines. These in turn promote antibody (Ab) secreting plasma cells which finally bind and inactivate the antigen.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Your doctor will decide the correct dose for you depending on your condition. Avoid drinking grapefruit juice while taking this medicine.

SIDE EFFECTS OF COMMUNE ME 50MG

SERIOUS

• Fever or sore throat
• Signs of brain infection (e.g. changes in sight, loss of coordination, memory loss, difficulty in speaking, muscle weakness)
• Feeling disorientated
• Feeling agitated, sleeplessness
• Coma, paralysis
• Stiff neck
• Swelling at the back of the eye
• Yellowing of skin and eyes
• Loss of appetite
• Dark-colored urine
• Problems in urination
• Pale skin, feeling tired
• Bruising or bleeding

COMMON

• High blood pressure
• Headache
• Tremor of your body
• Unwanted growth of body and facial hair
• Fits (seizures)
• Tiredness, loss of appetite
• Nausea, vomiting, abdominal pain, constipation, diarrhea
• Acne, hot flushes
• Fever
• Feeling numb or tingling
• Muscle pain
• Overgrowth of gum tissue

RARE

• Numbness or tingling in fingers and toes
• Severe upper stomach pain
• Swelling of face, stomach, hands, and/or feet
• Chest pain
• Changes in the menstrual cycle
• Breast enlargement in men