INTRODUCTION

DEFNET 24MG TABLET contains Deflazacort which belongs to the group of medicines called Anti-Inflammatory and Immunomodulator Drugs. It is used to treat inflammation in asthma (inflamed airways), arthritis (pain and inflammation in the joints), and allergies.

DEFNET 24MG TABLET is also used in the treatment of problems with your skin, kidney, heart, digestive system, eyes, or blood and where your body has growths (tumors). It is also used to prevent rejection after organ transplant operations.

DEFNET 24MG TABLET is not recommended for use in patients who have any untreated systemic infection and had any vaccinations with live viruses.

Before taking DEFNET 24MG TABLET, inform your doctor if you have epilepsy, problems in the liver, kidney, or heart, diabetes, high blood pressure, mental health problems, osteoporosis, glaucoma, esophagitis, ulcerative colitis, diverticulitis or peptic ulcer and pheochromocytoma.

DEFNET 24MG TABLET is generally not recommended for use in pregnant and breastfeeding women unless clearly advised by the doctor. DEFNET 24MG TABLET should be used with caution in children and elderly patients due to the increased risk of side effects.

The most common side effects of taking DEFNET 24MG TABLET are excessive facial hair, increased weight, skin redness, rash, nausea, and abdominal pain. Consult your doctor if any of the side effects worsen.

HOW DEFNET 24MG TABLET WORKS

DEFNET 24MG TABLET works by preventing the release of certain chemicals involved in the immune and allergic reactions, that result in inflammation. This type of action can reduce inflammation in a particular area, control various diseases characterized by excessive inflammation, and treats autoimmune disease conditions where the immune system attacks the body tissues. It also suppresses white blood cells along with an immune system to prevent the body from attacking foreign tissue in organ transplantation.

DIRECTIONS FOR USE

Take DEFNET 24MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Constipation:

Take fiber-rich foods in your diets such as fresh fruits, vegetables, and whole grain cereals, and drink plenty of fluids. Exercise more regularly (such as daily walking) and stay active. Consult your doctor if the symptom gets worse.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, consult your doctor.

WARNING & PRECAUTIONS

PREGNANCY

DEFNET 24MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking DEFNET 24MG TABLET.

BREASTFEEDING

DEFNET 24MG TABLET should be used with caution in breastfeeding women unless considered clearly necessary. Consult your doctor before taking DEFNET 24MG TABLET.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy or feel like everything around you is spinning or feel disorientated (vertigo) after taking DEFNET 24MG TABLET.

KIDNEY

DEFNET 24MG TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking DEFNET 24MG TABLET.

LIVER

DEFNET 24MG TABLET should be used with caution in patients with liver problems. Consult your doctor before taking DEFNET 24MG TABLET.

ALLERGY

Do not take DEFNET 24MG TABLET if you are allergic to Deflazacort. It should be used with caution in patients who have ever had a bad reaction such as muscle weakness to any steroids.

LUNGS

DEFNET 24MG TABLET should be used with caution in patients who had or have tuberculosis. Consult your doctor before taking DEFNET 24MG TABLET.

HEART DISEASE

DEFNET 24MG TABLET should be used with caution in patients with high blood pressure or heart problems. Consult your doctor before taking DEFNET 24MG TABLET.

Use in pediatrics:

DEFNET 24MG TABLET should be used with caution in children. Your child’s doctor may adjust the dose based on the child’s age and body and the dose may be initiated with the lowest effective dose. Consult your child’s doctor for advice.

Use in geriatrics:

DEFNET 24MG TABLET should be used with caution in elderly patients due to the increased risk of side effects. Consult your doctor before taking DEFNET 24MG TABLET.

INTERACTIONS

Drug-Drug interactions:

Before taking DEFNET 24MG TABLET, inform your doctor if you are taking any of the following medicines:

• Medicines used to relieve pain (Ex. aspirin, ibuprofen)
• Amino glutethimide (used for some types of cancer)
• Ketoconazole (used to treat fungal infections)
• Medicines used to remove excess water from the body (Ex. spironolactone, triamterene, or amiloride)
• Warfarin (used for thinning the blood)
• Medicines used in diabetes treatment (Ex. metformin or tolbutamide)
• Medicines used for epilepsy (Ex. phenobarbitone, primidone, phenytoin, carbamazepine, acetazolamide) Oral contraceptives such as estrogens (used to prevent pregnancy)
• Medicines used in tuberculosis treatment (Ex. rifampicin or rifabutin)
• Medicines used for treating high blood pressure (Ex. verapamil, atenolol, and propranolol)
• Medicines for indigestion and heartburn (Ex. aluminum hydroxide, magnesium carbonate, and calcium carbonate)
• Salbutamol and theophylline (used for asthma)

Overdo sage:

If you or anyone else accidentally takes too much of DEFNET 24MG TABLET, consult your doctor immediately or visit the nearby hospital.