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Halobetasol propionate is an idea to behave with the aid of using the induction of phospholipase A2 inhibitory proteins, together referred to as lipocortins. It is postulated that those proteins manipulate the biosynthesis of amazing mediators of irritation which includes prostaglandins and leukotrienes with the aid of using inhibiting the discharge in their not unusualplace precursor arachidonic acid. Arachidonic acid is launched from membrane phospholipids with the aid of using phospholipase A2. It is used for the comfort of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. A compound received from the bark of the white willow and wintergreen leaves and additionally organized synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
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