INTRODUCTION

SPRINTAS 50MG contains Cyclosporin which belongs to the group of medicines called immunosuppressive agents. Immunosuppressive agents are drugs that suppress or reduce the strength of the body’s immune system. It is used to prevent graft rejection in patients who have had an organ transplants, bone marrow, and stem cell transplantation.

It can also be used to treat various autoimmune diseases like severe rheumatoid arthritis, nephrotic syndrome (kidney disease), eye problems (endogenous uveitis, including Bechet's uveitis), and skin diseases (atopic dermatitis, or eczema and psoriasis). Cyclosporin blocks the development of cells that attack the affected transplanted tissue and suppress abnormal immune function thus preventing the rejection of transplanted organs.

Limit your exposure to sunlight and UV light by wearing protective clothing and by applying sunscreen to prevent skin cancer. Avoid the consumption of alcohol or grapefruit juice while taking this medicine. This medicine should not be given to children for any non-transplant disease, except for nephrotic syndrome. Do not take this medicine if you have any uncontrollable infection or any type of cancer. Consult your doctor for advice.

USES OF SPRINTAS 50MG

• Prevents the rejection of transplanted organs
• Treats severe rheumatoid arthritis
• Treats nephrotic syndrome (kidney disease)

HOW SPRINTAS 50MG WORKS

Cyclosporin works by inhibiting the production of various cytokines involved in the regulation of T-cell activation. These effects of cyclosporine on T cells and on connective tissue cells can produce a range of cytokines. These in turn promote antibody (Ab) secreting plasma cells which finally bind and inactivate the antigen.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Your doctor will decide the correct dose for you depending on your condition. Avoid drinking grapefruit juice while taking this medicine.

SIDE EFFECTS OF SPRINTAS 50MG

• Signs of brain infection (e.g. changes in sight, loss of coordination, memory loss, difficulty in speaking, muscle weakness)
• Confusion
• Nausea, vomiting, abdominal pain, constipation, diarrhea
• High blood pressure
• Problems in urination
• Yellowing of skin and eyes, Loss of appetite
• Bruising or bleeding
• Feeling numb or tingling
• Overgrowth of gum tissue

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after a meal. Stick to simple meals. Do not eat rich or spicy food.

Constipation:

Eat fiber-rich foods like fresh fruit, vegetables, and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids to avoid dehydration. Avoid taking any medicines for diarrhea without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and more frequent meals. Keeping a heating pad on your stomach may also help. If still pain persists, speak to your doctor.

ALCOHOL

Avoid consumption of alcohol while taking this medicine, as it may increase the risk of side effects.

KIDNEY

Do not take SPRINTAS 50MG if you are suffering from severe kidney disease. Consult your doctor for advice.

Can SPRINTAS 50MG cause cancer?

Yes. This medicine increases your risk of developing cancers, particularly of the skin and lymphoid system. Limit your exposure to sunlight and UV light by wearing appropriate protective clothing and applying sunscreen with a high protection factor often while taking this medicine.